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Case Four - Atrophy of the Liver


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Clinical History: Patient with renal transplant developed malignant sarcoma with metastatic disease of the liver. Two progress studies are demonstrated.

Findings: First scan shows the most recent study which shows a metastatic site in the right lobe and a very thin left lobe. Etiology of the left lobe was not understood until the earlier study was found. The earlier study (second scan) shows a metastatic site in the left lobe which apparently reduced in size after chemotherapy and produced the appearance as noted. Also note the small atrophied natural kidneys in their normal location.

Diagnosis: Atrophy of the parenchyma of the left lobe of the liver, following chemotherapy.

Discussion: It is quite common to see reduction in the size of liver lesions following successful chemotherapy, but atrophy of the normal liver is uncommon. In this case the tumor mass produced enlargement and effacement of the adjacent normal liver. During tumor growth, the normal liver was apparently compromised by pressure. After the tumor reduced in size crom chemotherapy, the normal liver was left in a very attenuated configuration.

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Submitted by:
John R. Haaga, M.D.
Chairman - Dept. of Radiology